| leader | | CAICEDO CEPEDA Jonathan Klever | | EF1 | | | | 6 | |
| 1. | | EF Pro Cycling | | 18'01" | | 5 | |
| CAICEDO CEPEDA Jonathan Klever, HIGUITA GARCIA Sergio Andres, VAN GARDEREN Tejay, MARTINEZ POVEDA Daniel Felipe | |
| 2. | | Deceuninck - Quick Step | | 45" | | 2 | |
| ALAPHILIPPE Julian, JUNGELS Bob, VAN LERBERGHE Bert, STEIMLE Jannik | |
| 3. | | INEOS Grenadiers | | 46" | | 1 | |
| BERNAL GOMEZ Egan Arley, CARAPAZ MONTENEGRO Richard Antonio, NARVAEZ PRADO Jhonatan Manuel, RIVERA VARGAS Brandon Smith | |
| 4. | | Rally Cycling | | 59" | | 0 | |
| CARPENTER Robin, MANNION Gavin, MURPHY Kyle, JOYCE Colin | |
| 5. | | UAE Team Emirates | | 01'00" | | 0 | |
| ARU Fabio, MUÑOZ LANCHEROS Cristian Camilo, HENAO MONTOYA Sergio Luis, MOLANO BENAVIDES Juan Sebastian | |
| 6. | | EPM - Scott | | 01'00" | | 0 | |
| GIL SANCHEZ Angel Alexander, CHAVES TORRES German Enrique, OCHOA CAMARGO Diego Antonio, REYES ORTEGA Aldemar, MONTAÑA CADENA Fredy Emir, SUAREZ SUAREZ Juan Pablo | |
| 7. | | Movistar Team | | 01'02" | | 0 | |
| SEPULVEDA Eduardo, JORGENSON Matteo, ALBA BOLIVAR Juan Diego, BETANCUR GOMEZ Carlos Alberto | |
| 8. | | Israel Start-Up Nation | | 01'21" | | 0 | |
| AVILA VANEGAS Edwin Alcibiades, BADILATTI Matteo, SCHELLING Patrick, TUREK Daniel | |
| 9. | | Team Medellin | | 01'24" | | 0 | |
| SEVILLA RIVERA Oscar Miguel, DUARTE AREVALO Fabio Andres, SANCHEZ VERGARA Brayan Stiven, HERNANDEZ JARAMILLO Jose Tito | |
| 10. | | Uno-X Pro Cycling Team | | 01'32" | | 0 | |
| SAUGSTAD Lars, HVIDEBERG Jonas Iversby, ANDERSEN Idar, TRAEEN Torstein | |